Pharmaceutical film coating may become a new hot spot in the industry
Introduction: Film coating machine is an indispensable mechanical equipment for the development of modern pharmaceutical industry. Although it has only started to develop in my country in recent years, it has developed rapidly with its many advantages and has become the pharmaceutical industry. The "new hot spot" has made a great contribution to the health of the masses of people in modern society.
Film coating is a new type of coating technology, which refers to a relatively stable thin layer of polymer coating film on the outside of the tablet core. The film coating process can be widely used in tablets, pills, and granules, especially for Chinese medicine tablets with strong hygroscopicity, easy cracking, and variegation. It can be seen that in the field of medicine, medicinal film coating The role of is becoming more and more important. From a professional point of view, medicinal film coating is a layer of polymer film covering the surface of medicines, which has various functions such as coloring, beautifying and controlling the efficacy of medicines. The principle of medicinal film coating is relatively simple, but the film forming process is quite complicated. In the existing medicinal film coating, the coating material is usually formed into a film by a spray process in a dispersion system (including water solvent and organic solvent). When the dispersion system of the polymer material is atomized by the spray gun and sprayed on the surface of the drug with tiny droplets, these small droplets are quickly spread on the surface of the drug under the action of surface tension and friction, and are taken away by the heat of hot air. The solvent quickly forms a film.
The technology of medicinal film coating is largely developed from sugar coating, but compared with it, medicinal film coating has the advantages of good quality, fast drying, low pollution, low cost, and wide application. Although the price of film coating materials is more expensive than sugar and talc, due to the small amount and labor saving (1 to 2 operators), less plant and equipment are required (only one standard plant and one coating pan). It saves materials and energy, so the overall calculation is not higher than the cost of sugar coating. Moreover, the process can reduce or avoid dust flying in the workshop, which is beneficial to environmental protection and labor protection, and at the same time can prevent pollution in the workshop, which is of great significance for meeting GMP clean requirements under dynamic conditions.
With the scientific development of polymer materials in recent years, the film coating liquid has been improved, the products are diversified, and show the development trend of water solubility and high concentration. The improvement of coating materials and coating technology is also imperative. In this regard, enterprises need to explore in many aspects, give full play to the advantages of film coating, make up for their own shortcomings, and enable them to develop with the market.